Julia Steffen

Deficiency of actin depolymerizing factors ADF/Cfl1 in microglia decreases motility and impairs memory

This study shows that ADF/Cfl1 deficiency in microglia reduces motility and impairs memory by affecting cytoskeleton dynamics.

CX3CR1 modulates migration of resident microglia towards brain injury

This study shows that CX3CR1 deficiency enhances microglial migration towards brain injury, suggesting it as a potential therapeutic target for CNS injuries.

Microglia motility depends on neuronal activity andpromotes structural plasticity in the hippocampus

This study shows that microglia motility depends on neuronal activity and promotes synaptic plasticity in the hippocampus of awake mice.

Hippocampal hyperactivity in a rat model of Alzheimers disease

The paper investigates hippocampal neuronal activity in a rat Alzheimer's disease model, finding hyperactivity and intrinsic excitability changes in CA1 neurons before synaptic inhibition is affected.

Network fingerprint of stimulation induced speech impairment in essential tremor

The paper identifies structural brain fibers associated with speech impairment caused by deep brain stimulation in essential tremor patients and shows their predictive value for intelligibility changes.

Memory trace superimposition impairs recall in a mouse model of AD

The paper shows that in a mouse model of AD, memory recall is impaired due to the superimposition of new neurons onto the memory trace during retrieval.

Restoring memory by optogenetic synchronization of hippocampal oscillations in an Alzheimer’s disease mouse model

The paper restores memory in Alzheimer’s disease mice by optogenetically synchronizing hippocampal theta oscillations.