Author

Kerstin Hoffmann

German Center for Neurodegenerative Diseases

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Organism:rat· 1

Frequent Co-Authors

A. Claudio CuelloiD· 1 shared Anders BrunseiD· 1 shared Anna Hammerich ThyseniD· 1 shared Bernd SchmeckiD· 1 shared Björn KlabundeiD· 1 shared Bo ChawesiD· 1 shared Daniel JustusiD· 1 shared Detlef Friedrichs· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

A. Claudio CuelloORCID

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2 papers

Recent·Most cited

Ketone and glycolytic metabolism are key modulators of inflammation during neonatal sepsis

Björn Klabunde, Ole Bæk, Karoline Aasmul Olsen, Anna Hammerich Thysen, Margret Gudbrandsdottir, Katrin Laakmann, Kerstin Hoffmann, Bernd Schmeck, Anders Brunse, Nguyen Phuoc Long, Quoc Viet Le, Susanne Brix, Bo Chawes, Duc Ninh Nguyen

This study shows that inhibiting glycolysis or supplementing ketones can reduce inflammation and improve outcomes in neonatal sepsis by enhancing mitochondrial metabolism and disease tolerance.

bioRxiv · Aug 15, 2025 · PreprintImmunology

Hippocampal hyperactivity in a rat model of Alzheimers disease

Liudmila Sosulina, Manuel Mittag, Hans‐Rüdiger Geis, Kerstin Hoffmann, Igor V. Klyubin, Yingjie Qi, Julia Steffen, Detlef Friedrichs, Niklas Henneberg, Falko Fuhrmann, Daniel Justus, Kevin Keppler, A. Claudio Cuello, Michael J. Rowan, Martin Fuhrmann, Stefan Remy

The paper investigates hippocampal neuronal activity in a rat Alzheimer's disease model, finding hyperactivity and intrinsic excitability changes in CA1 neurons before synaptic inhibition is affected.

Journal of Neurochemistry · Feb 14, 2021Peer-reviewedNeuroscience