Estimating parasite load dynamics to reveal novel resistance mechanisms to human malaria
Michael T. Bretscher, Athina Georgiadou, Hyun Jae Lee, Michael R. Walther, Anna E. van Beek, Fadlila Fitriani, Diana Wouters, Taco Willem Kuijpers, Davis C. Nwakanma, Umberto D’Alessandro, Eleanor M. Riley, Michael Levin, Lachlan Coin, Azra C. Ghani, David J. Conway, Aubrey J. Cunnington
The paper estimates parasite load dynamics in malaria to identify host resistance mechanisms, finding novel roles for proteases and detrimental effects of interferon response.
bioRxiv · May 15, 2018 · PreprintSystems Biology