Author

Dimple Nagesh

Indian Institute of Science Bangalore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Pathology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

Amarjeet Shrama· 3 shared Bhoomika Shivanaiah· 3 shared Nagalingam Ravi SundaresaniD· 3 shared Aastha Munjal· 2 shared Arathi Bangalore Prabhashankar· 2 shared Sukanya RaghuiD· 2 shared Thoniparambil Sunil Sumi· 2 shared Abhishek ChowdhuryiD· 1 shared

Activity by Year

2025-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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3 shared papersPhysiology

Amarjeet Shrama

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Author profile →

3 papers

Recent·Most cited

PARP1 deficiency induces aging-associated cardiac failure via activation of Akt signalling

Thoniparambil Sunil Sumi, Sneha Mishra, Amarjeet Shrama, Abhishek Chowdhury, Bhoomika Shivanaiah, Dimple Nagesh, Souvik Roy, Aastha Munjal, Ashwini Yogilal Bhelave, Kumaravel Somasundaram, Nagalingam Ravi Sundaresan

This study shows PARP1 deficiency causes aging-related cardiac failure by activating Akt signaling, leading to hypertrophy and fibrosis in mice.

bioRxiv · Dec 4, 2025 · PreprintPhysiology

SIRT2 attenuates stress-induced skeletal muscle atrophy by inhibiting glucocorticoid receptor signaling

Ankit Kumar Tamta, Bhoomika Shivanaiah, Arathi Bangalore Prabhashankar, Sunayana Ningaraju, Seemadri Subhadarshini, Anurag Nagaraja Sharma, Harsha Mambully Jayaprakasan, Meera Krishnan E R, Apeksha Bhuyar, Devika Sunil, Amarjeet Shrama, Dimple Nagesh, Aastha Munjal, Sukanya Raghu, Manepalli Bhavya Madhuri, , Nagalingam Ravi Sundaresan

This study identifies SIRT2 as a regulator of stress-induced skeletal muscle atrophy by inhibiting glucocorticoid receptor signaling, showing protective effects in mice.

bioRxiv · Oct 22, 2025 · PreprintPathology

Sirtuin 2 controls global protein synthesis by regulating Rheb-GTPase

Amarjeet Shrama, Yanlin Zi, Anwit Shriniwas Pandit, Kirtika Jha, Vikrant Kumar Sinha, Venkatraman Ravi, Souvik Ghosh, Dimple Nagesh, Bhoomika Shivanaiah, Danish Khan, Arathi Bangalore Prabhashankar, Thoniparambil Sunil Sumi, Sukanya Raghu, Anand Kumar Srivastava, Mahavir Singh, , Nagalingam Ravi Sundaresan

This study identifies SIRT2 as a regulator of global protein synthesis by modulating Rheb-GTPase activity, showing its potential as a therapeutic target for diseases with increased protein synthesis.

bioRxiv · Mar 31, 2025 · PreprintCell Biology