Author

Kirtika Jha

Indian Institute of Science Bangalore

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:deep learning· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Assay:metagenomics· 1 Organism:mouse· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Anand Kumar SrivastavaiD· 2 shared Amarjeet Shrama· 1 shared Anwit Shriniwas PanditiD· 1 shared Arathi Bangalore Prabhashankar· 1 shared Bhoomika Shivanaiah· 1 shared Danish KhaniD· 1 shared Dimple Nagesh· 1 shared Hening LiniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersBiophysics

Anand Kumar SrivastavaORCID

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2 papers

Recent·Most cited

Phosphoinositides protonation states dictate AKT1 binding with membrane

Kirtika Jha, M. Z. I. Sarkar, Krishnakanth Baratam, Jayashree Nagesh, Thomas John Pucadyil, Anand Srivastava

This study shows that phosphoinositide protonation microstates determine AKT1 membrane binding specificity and how mutations alter this interaction.

bioRxiv · Sep 10, 2026 · PreprintBiophysics

Sirtuin 2 controls global protein synthesis by regulating Rheb-GTPase

Amarjeet Shrama, Yanlin Zi, Anwit Shriniwas Pandit, Kirtika Jha, Vikrant Kumar Sinha, Venkatraman Ravi, Souvik Ghosh, Dimple Nagesh, Bhoomika Shivanaiah, Danish Khan, Arathi Bangalore Prabhashankar, Thoniparambil Sunil Sumi, Sukanya Raghu, Anand Kumar Srivastava, Mahavir Singh, , Nagalingam Ravi Sundaresan

This study identifies SIRT2 as a regulator of global protein synthesis by modulating Rheb-GTPase activity, showing its potential as a therapeutic target for diseases with increased protein synthesis.

bioRxiv · Mar 31, 2025 · PreprintCell Biology