Disentangling gene expression burden identifies generalizable phenotypes induced by synthetic gene networks
Aqib Hasnain, Amin Espah Borujeni, Yongjin Park, Diveena Becker, Paul Maschhoff, Joshua A. Urrutia, Linus Rydell, Shara Balakrishnan, Yuval Dorfan, Christopher A. Voigt, Enoch Yeung
The paper identifies synthetic gene network-induced phenotypes by analyzing gene expression in E. coli and validates them through antibiotic resistance experiments.
bioRxiv · Jun 29, 2023 · PreprintSystems Biology