Author

Dominique Paul

University of Zurich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Pierre‐Luc GermainiD· 2 shared Ahmad Al-AjamiiD· 1 shared Aleksandra L. PtaszekiD· 1 shared Almut LuetgeiD· 1 shared Andreas R. HierlemanniD· 1 shared Anthony SonreliD· 1 shared Charlotte SonesoniD· 1 shared Elyas HeidariiD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMolecular Biology

Pierre‐Luc GermainORCID

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Author profile →

2 papers

Recent·Most cited

Harnessing PROTAC technology to combat stress hormone receptor activation

Mahshid Gazorpak, Karina M. Hugentobler, Dominique Paul, Pierre‐Luc Germain, Miriam Kretschmer, Iryna Ivanova, Selina Frei, Kei H Mathis, Remo Rudolf, Sergio Mompart Barrenechea, Vincent Fischer, Xiaohan Xue, Aleksandra L. Ptaszek, Julian Holzinger, Mattia Privitera, , Katharina Gapp

This paper introduces a novel GR degrader, KH-103, which selectively degrades glucocorticoid receptors and shows improved efficacy over existing inhibitors.

Nature Communications · Dec 9, 2023Peer-reviewedMolecular Biology

Meta-analysis of (single-cell method) benchmarks reveals the need for extensibility and interoperability

Anthony Sonrel, Almut Luetge, Charlotte Soneson, Izaskun Mallona, Pierre‐Luc Germain, Sergey Knyazev, Jeroen Gilis, Reto Gerber, Ruth Seurinck, Dominique Paul, Emanuel Sonder, Helena Lucia Crowell, Imran Fanaswala, Ahmad Al-Ajami, Elyas Heidari, , Mark D. Robinson

This paper meta-analyzes single-cell method benchmarks to identify challenges in extensibility, interoperability, and reproducibility.

bioRxiv · Sep 22, 2022 · PreprintBioinformatics