Xiaohan Xue

This paper introduces a novel GR degrader, KH-103, which selectively degrades glucocorticoid receptors and shows improved efficacy over existing inhibitors.

The paper develops an experimental platform to analyze excitatory and inhibitory synaptic inputs in neurons and finds that spiking coincides with rapid changes in the E/I ratio.

This paper introduces a multi-modal fitting framework combining patch-clamp and HD-MEA data to build more accurate multicompartment neuron models.

The paper introduces a method to identify monosynaptic connections using dendritic spine Ca2+ imaging and extracellular spiking recordings, validated with simulations.

This paper introduces an automated method to reconstruct axons and estimate action-potential propagation velocities from high-density microelectrode array recordings.