Cross-Species Efficacy of Combinatorial Gene Therapy for Osteoarthritis and Correction of Neuro-Inflammatory Pain Mechanisms
Erica J. Secor, Jun Wang, Zelong Dou, Jiansen Yan, Camilla F. Majano, Matthew J. Woodman, Oscar Ruiz, Joud Al Azaat, Duncan Crosby, Racel Cela, Sarah L. Pownder, Julie B. Engiles, Donna Palmer, Ming‐Ming Jiang, Carolina Leynes, , Brendan Lee
A combinatorial gene therapy targeting inflammation and chondrocyte health slows OA progression and reduces pain in murine and equine models.
bioRxiv · Jul 28, 2026 · PreprintSystems Biology