Author

Oscar Ruiz

Baylor College of Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 1 Neuroscience· 1 Physiology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Organism:human· 1 Assay:imaging· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Brendan LeeiD· 4 shared Jiansen YaniD· 4 shared Racel Cela· 4 shared Yangjin BaeiD· 4 shared Zelong DouiD· 4 shared Benjamin Russell ArenkieliD· 3 shared Camilla F. Majano· 3 shared Nele A.T HaeltermaniD· 3 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersSystems Biology

Brendan LeeORCID

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Author profile →

4 papers

Recent·Most cited

Cross-Species Efficacy of Combinatorial Gene Therapy for Osteoarthritis and Correction of Neuro-Inflammatory Pain Mechanisms

Erica J. Secor, Jun Wang, Zelong Dou, Jiansen Yan, Camilla F. Majano, Matthew J. Woodman, Oscar Ruiz, Joud Al Azaat, Duncan Crosby, Racel Cela, Sarah L. Pownder, Julie B. Engiles, Donna Palmer, Ming‐Ming Jiang, Carolina Leynes, , Brendan Lee

A combinatorial gene therapy targeting inflammation and chondrocyte health slows OA progression and reduces pain in murine and equine models.

bioRxiv · Jul 28, 2026 · PreprintSystems Biology

Sequential intra-articular HCAd-NFκB-IL-1Ra delivery improves therapeutic efficacy in post-traumatic osteoarthritis

Jiansen Yan, Zelong Dou, Camilla F. Majano, Racel Cela, Ming‐Ming Jiang, Syed Shayan Mehdi, Joud Al Azaat, Duncan Crosby, Amanda Rosewell Shaw, Lisa A. Yuva‐Paylor, Surabi Veeraragavan, Oscar Ruiz, Donna J. Palmer, Philip Ng, Nele A.T Haelterman, , Brendan Lee

This study shows that switching adenovirus serotypes for repeated gene therapy in osteoarthritis improves cartilage preservation but not functional outcomes.

bioRxiv · Jul 28, 2026 · PreprintMolecular Biology

A standardized, open-source, portable model for noninvasive joint injury in mice

Michael D. Newton, Lindsey Lammlin, Sofia Gonzalez-Nolde, Scarlet C. Howser, Isabelle Smith, Luke Stasikelis, Alexander J. Knights, Armen N. Akopian, Kyle Allen, Alejandro Almarza, Benjamin Russell Arenkiel, Maryam Aslam, Başak Dönertaş Ayaz, Yangjin Bae, Bruna Balbino de Paula, , Julia Younis

The paper introduces a standardized, open-source protocol for noninvasive joint injury in mice, resulting in post-traumatic osteoarthritis, and provides tools for reproducibility and analysis.

Osteoarthritis and Cartilage Open · Sep 17, 2025Peer-reviewedPhysiology

Identification of Sensory Fiber Types in Mouse Temporomandibular Joint Tissues

Jessie J. Alfaro, Exing Wang, Kyle M. Allen, Alejandro J. Almarza, Benjamin Russell Arenkiel, Başak Dönertaş Ayaz, Yangjin Bae, Bruna Balbino de Paula, Anita E. Bandrowski, Mario Danilo Boada, Jacqueline B Boccanfuso, Jyl Boline, Dellina Lane Carpio, Dawen Cai, Robert M. Caudle, , Armen N. Akopian

This study identifies sensory fiber types in mouse TMJ tissues using immunohistochemistry, finding peptidergic fibers dominate with minimal non-peptidergic nociceptors.

Scientific Reports · Sep 1, 2025Peer-reviewedNeuroscience