SOD1 Mediates Lysosome-to-Mitochondria Communication and its Dysregulation by Amyloid-β Oligomers
Andrés Norambuena, Xuehan Sun, Horst K. Wallrabe, Ruofan Cao, Naidi Sun, Evelyn Pardo, Nutan Shivange, Dora Bigler Wang, Lisa A. Post, Heather Anne Ferris, Song Hu, Ammasi Periasamy, George S. Bloom
The paper identifies SOD1 as a mediator of lysosome-to-mitochondria communication and shows its dysregulation by amyloid-β oligomers in Alzheimer's disease.
Neurobiology of Disease · Apr 20, 2022Peer-reviewedNeuroscience