Author

E. A. Vilas-Boas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:metabolism & bioenergetics· 4 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:metabolomics· 2 Organism:rat· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

A. J. Kowaltowski· 4 shared C. C. Caldeira da Silva· 2 shared J. V. Cabral-Costa· 2 shared A. Bruni-Cardoso· 1 shared A. C. Manucci· 1 shared A. C. Munhoz· 1 shared D. S. Rocha· 1 shared F. C. Mosele· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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4 shared papersBiochemistry

A. J. Kowaltowski

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A practical and robust method to evaluate metabolic fluxes in pancreatic islets

D. S. Rocha, A. C. Manucci, A. Bruni-Cardoso, A. J. Kowaltowski, E. A. Vilas-Boas

This paper develops a practical and robust method to assess primary pancreatic islet metabolic fluxes using standard Seahorse equipment, showing reliable respiration and functional responses in mouse and rat islets.

bioRxiv · Jul 25, 2023 · PreprintBiochemistry

Mitochondrial Sodium/Calcium Exchanger (NCLX) Regulates Basal and Starvation-Induced Autophagy Through Calcium Signaling

V. de Miranda Ramos, J. D. Serna, E. A. Vilas-Boas, J. V. Cabral-Costa, F. M. da Cunha, T. Kataura, V. I. Korolchuk, A. J. Kowaltowski

This study shows that NCLX regulates autophagy via calcium signaling, with NCLX knockdown impairing basal and starvation-induced autophagy.

bioRxiv · Mar 17, 2023 · PreprintCell Biology

Adiponectin Reverses Beta-Cell Damage and Impaired Insulin Secretion Induced by Obesity

A. C. Munhoz, J. D. C. Serna, E. A. Vilas-Boas, C. C. Caldeira da Silva, T. G. dos Santos, F. C. Mosele, S. L. Felisbino, V. R. Martins, A. J. Kowaltowski

This study shows that adiponectin protects beta-cells from obesity-induced damage and restores insulin secretion by reversing mitochondrial dysfunction and oxidative phosphorylation impairment.

bioRxiv · Jul 22, 2022Biochemistry

Goldilocks calcium and the mitochondrial respiratory chain: too much, too little, just right

E. A. Vilas-Boas, J. V. Cabral-Costa, V. M. Ramos, C. C. Caldeira da Silva, A. J. Kowaltowski

This study quantifies how different calcium concentrations affect mitochondrial respiration in mouse liver mitochondria and hepatocytes, finding an optimal range for oxidative phosphorylation.

bioRxiv · Apr 12, 2022 · PreprintBiochemistry