Author

J. V. Cabral-Costa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:metabolism & bioenergetics· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. J. Kowaltowski· 3 shared E. A. Vilas-Boas· 2 shared A. Almeida· 1 shared C. C. Caldeira da Silva· 1 shared C. Vicente-Gutierrez· 1 shared F. M. da Cunha· 1 shared J. Agulla· 1 shared J. D. Serna· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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3 shared papersBiochemistry

A. J. Kowaltowski

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Mitochondrial Sodium/Calcium Exchanger (NCLX) Regulates Basal and Starvation-Induced Autophagy Through Calcium Signaling

V. de Miranda Ramos, J. D. Serna, E. A. Vilas-Boas, J. V. Cabral-Costa, F. M. da Cunha, T. Kataura, V. I. Korolchuk, A. J. Kowaltowski

This study shows that NCLX regulates autophagy via calcium signaling, with NCLX knockdown impairing basal and starvation-induced autophagy.

bioRxiv · Mar 17, 2023 · PreprintCell Biology

Mitochondrial sodium/calcium exchanger NCLX regulates glycolysis in astrocytes, impacting on cognitive performance

J. V. Cabral-Costa, C. Vicente-Gutierrez, J. Agulla, R. Lapresa, J. W. Elrod, A. Almeida, J. P. Bolanos, A. J. Kowaltowski

This study shows that NCLX in astrocytes affects glycolysis and cognitive performance, with different impacts based on cell type.

bioRxiv · Sep 16, 2022Biochemistry

Goldilocks calcium and the mitochondrial respiratory chain: too much, too little, just right

E. A. Vilas-Boas, J. V. Cabral-Costa, V. M. Ramos, C. C. Caldeira da Silva, A. J. Kowaltowski

This study quantifies how different calcium concentrations affect mitochondrial respiration in mouse liver mitochondria and hepatocytes, finding an optimal range for oxidative phosphorylation.

bioRxiv · Apr 12, 2022 · PreprintBiochemistry