E. Bianchi

Deep learning insights into the architecture of the mammalian egg-sperm fusion synapse

The paper uses AlphaFold-Multimer to predict a pentameric complex involved in mammalian egg-sperm fusion, including TMEM81, a previously uncharacterized sperm protein.

Camouflaging Endovascular Stents with an Endothelial Coat Using CD31 Domain 1-mimetic Peptides

This study coats endovascular stents with CD31 domain 1-mimetic peptides to promote endothelial integration and reduce blood cell activation, showing improved device integration and neo-arterial wall formation over 60 days.

Mutated clones driving leukemic transformation are already detectable at the single cell level in CD34-positive cells in the chronic phase of primary myelofibrosis

The paper uses single cell genomics and transcriptomics to analyze CD34-positive cells in a PMF patient, identifying early mutations and clonal evolution associated with AML transformation.