IL-1RA Disrupts ATP Activation of P2RX7 in Human Monocyte-Derived Microglia-like Cells
K. S. Heavener, K. Kabra, M. Yidenk, E. Bradshaw
This study shows that P2RX7 in human microglia-like cells mediates ATP-induced cytokine production and amyloid-beta uptake, and its function is modulated by IL-1 signaling.
bioRxiv · Apr 8, 2024 · PreprintImmunology