Author

P. Gaur

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Biophysics· 2 Cell Biology· 2 Biochemistry· 1 Immunology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 9 Organism:human· 5 Research Focus:cell type annotation· 4 Organism:mouse· 3 Assay:proteomics· 3 Approach:biophysical modeling· 2 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2

Frequent Co-Authors

M. Honda· 3 shared M. Spies· 3 shared A. B. Yadav· 2 shared M. Razzaghi· 2 shared P. Yadav· 2 shared S. L. Granger· 2 shared A. Bajaj· 1 shared A. Jarjoui· 1 shared

Activity by Year

2019-2023 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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3 shared papersBiophysics

M. Honda

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

A double-ring of human RAD52 remodels replication forks restricting fork reversal

M. Honda, M. Razzaghi, P. Gaur, E. Malacaria, G. Marozzi, L. Di Biagi, F. A. Aiello, E. A. Paintsil, A. Stanfield, B. J. Deppe, L. Gakhar, N. J. Schnicker, M. A. Spies, P. Pichierri, M. Spies

The paper shows human RAD52 forms a double-ring structure around stalled replication forks, remodeling them via DNA strand exchange to prevent reversal by SMARCAL1.

bioRxiv · Nov 14, 2023 · PreprintBiochemistry

Human hnRNPA1 reorganizes telomere-bound Replication Protein A

S. L. Granger, R. Sharma, V. Kaushik, M. Razzaghi, M. Honda, P. Gaur, D. S. Bhat, S. M. Labenz, J. E. Heinen, B. A. Williams, A. Tabei, M. Wlodarski, E. Antony, M. Spies

The paper shows hnRNPA1 remodels RPA bound to telomeric ssDNA, forming a ternary complex regulated by TERRA.

bioRxiv · May 9, 2023Biophysics

Single-molecule analysis of the improved variants of the G-quadruplex recognition protein G4P

P. Gaur, F. E. Bain, M. Honda, S. L. Granger, M. Spies

The paper analyzes the binding kinetics and selectivity of G4P and its variants using single-molecule techniques, finding that increasing RSM units enhances affinity for telomeric G4s.

bioRxiv · May 8, 2023 · PreprintBiophysics

Rab7 dependent regulation of goblet cell protein CLCA1 modulates gastrointestinal homeostasis

P. Gaur, Y. Rajendran, B. Srivastava, M. Markandey, V. Fishbain-Yoskovitz, G. Mohapatra, A. Suhail, S. Chaudhary, S. Tyagi, S. C. Yadav, A. K. Pandey, Y. Merbl, A. Bajaj, V. Ahuja, C. Srikanth

This study shows Rab7 regulates CLCA1 in goblet cells, affecting mucus composition and gut microbiota, leading to increased susceptibility to colitis.

bioRxiv · Feb 13, 2023Cell Biology

COVID-19 patients have increased levels of membrane-associated and soluble CD48

H. Pahima, I. Zaffran, E. Ben-Chetrit, A. Jarjoui, P. Gaur, M. L. Manca, D. Reichmann, E. Orenbuch-Harroch, I. Puxeddu, C. Zinner, A. Tzankov, F. Levi-Schaffer

The paper finds increased levels of membrane-bound and soluble CD48 in COVID-19 patients through various assays, suggesting a potential therapeutic target.

bioRxiv · Mar 18, 2022 · PreprintImmunology

Unique Microglial Transcriptomic Signature within the Hippocampal Neurogenic Niche

S. Chintamen, P. Gaur, N. Vo, E. Bradshaw, V. Menon, S. G. Kernie

The paper identifies a unique microglial transcriptomic signature in the hippocampal neurogenic niche, showing increased phagocytosis and overlap with disease-associated microglia.

bioRxiv · Aug 29, 2021 · PreprintCell Biology

Protein stability and functional activity during nebulization: A comparative study of three nebulizer!

N. Singh, P. Yadav, P. Gaur, M. Gaur, A. B. Yadav

This study compares three nebulizers for protein delivery, showing that compressed air nebulizer delivers more precise small amounts of protein but compromises stability more than mesh nebulizer.

bioRxiv · May 9, 2020 · PreprintBioengineering

Bioengineered ciprofloxacin loaded chitosan nanoparticles for the treatment of Bovine Mastitis

P. Yadav, P. Gaur, A. B. Yadav, Z. I. Huma, N. Sharma

The paper demonstrates ciprofloxacin-loaded chitosan nanoparticles as an effective treatment for bovine mastitis by improving drug availability and antimicrobial activity against E. coli and S. aureus.

bioRxiv · May 9, 2020Pharmacology & Toxicology

Histologic safety of transcranial focused ultrasound neuromodulation and magnetic resonance acoustic radiation force imaging in rhesus macaques and sheep

P. Gaur, K. M. Casey, J. Kubanek, N. Li, M. Mohammadjavadi, Y. Saenz, G. H. Glover, D. M. Bouley, K. Butts Pauly

This study evaluates the histologic safety of transcranial focused ultrasound neuromodulation and MR-ARFI in rhesus macaques and sheep, finding no FUS-related tissue damage.

bioRxiv · Nov 1, 2019Bioengineering