Author

E. C. Pratt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Assay:imaging· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Organism:human· 1

Frequent Co-Authors

D. Bauer· 2 shared J. Grimm· 2 shared J. S. Lewis· 2 shared A. Bell· 1 shared A. H. Otake· 1 shared A. Michel· 1 shared B. M. Larney· 1 shared C. M. Machado· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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2 shared papersPharmacology & Toxicology

D. Bauer

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Exploring the PET in vivo generator 134Ce as a theranostic match for 225Ac

D. Bauer, R. De Gregorio, E. C. Pratt, A. Bell, A. Michel, J. S. Lewis

This paper compares 225Ac and 134Ce-labeled tracers in cancer models to assess their suitability as a theranostic pair, finding that 134Ce's PET imaging is limited by daughter nuclide redistribution.

bioRxiv · Apr 25, 2024 · PreprintPharmacology & Toxicology

Radiances of Cerenkov-Emitting Isotopes on the IVIS

E. C. Pratt, T. M. Shaffer, D. Bauer, J. S. Lewis, J. Grimm

The paper presents the largest experimental dataset of Cerenkov-emitting isotopes measured using IVIS, providing normalized radiance values for 21 isotopes across various emissions.

bioRxiv · Jan 18, 2023 · PreprintBioengineering

PSMA-bearing extracellular vesicles secreted from prostate cancer convert the microenvironment to a tumor-supporting, pro-angiogenic state.

C. M. Machado, M. Skubal, K. Haedicke, F. S. Pittela, E. P. Stater, B. M. Larney, T. L. A. O. Silva, E. T. Costa, C. Masotti, A. H. Otake, L. N. S. Andrade, M. S. Junqueira, H.-T. Hsu, S. Das, E. C. Pratt, , J. Grimm

The paper shows that PSMA-bearing extracellular vesicles from prostate cancer cells promote a pro-angiogenic tumor microenvironment by increasing VEGF-A, angiogenin, and 4EBP-1 phosphorylation.

bioRxiv · Feb 25, 2022 · PreprintCancer Biology