Author

M. Skubal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cancer & tumor microenvironment· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. Grimm· 3 shared A. Ogirala· 2 shared B. E. Mc Larney· 2 shared H.-T. Hsu· 2 shared A. H. Otake· 1 shared A. Volpe· 1 shared A.-V. Dozic· 1 shared B. M. Larney· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersCancer Biology

J. Grimm

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Vascularized tumor on a microfluidic chip to study mechanisms promoting tumor neovascularization and vascular targeted therapies

M. Skubal, B. E. Mc Larney, N. B. Phung, J. C. Desmaras, A.-V. Dozic, A. Volpe, A. Ogirala, C. M. L. Machado, J. Djibankov, V. Ponomarev, J. Grimm

This study develops a microfluidic chip model of vascularized tumors to evaluate angiogenesis and vascular-targeted therapies, showing bevacizumab disrupts tumor-vessel interactions and enables rapid drug assessment.

bioRxiv · Aug 7, 2023Cancer Biology

Preclinical shortwave infrared tumor screening and resection via pHLIP ICG under ambient lighting conditions

B. E. Mc Larney, M. Kim, S. Roberts, M. Skubal, H.-T. Hsu, A. Ogirala, N. PILLARSETTY, D. A. Heller, J. S. Lewis, J. Grimm

This study demonstrates that SWIR imaging with pHLIP ICG enables sensitive tumor detection and resection under ambient lighting conditions in a preclinical breast cancer model.

bioRxiv · Sep 7, 2022Cancer Biology

PSMA-bearing extracellular vesicles secreted from prostate cancer convert the microenvironment to a tumor-supporting, pro-angiogenic state.

C. M. Machado, M. Skubal, K. Haedicke, F. S. Pittela, E. P. Stater, B. M. Larney, T. L. A. O. Silva, E. T. Costa, C. Masotti, A. H. Otake, L. N. S. Andrade, M. S. Junqueira, H.-T. Hsu, S. Das, E. C. Pratt, , J. Grimm

The paper shows that PSMA-bearing extracellular vesicles from prostate cancer cells promote a pro-angiogenic tumor microenvironment by increasing VEGF-A, angiogenin, and 4EBP-1 phosphorylation.

bioRxiv · Feb 25, 2022 · PreprintCancer Biology