Author

E. G. Dora

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5

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Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 5 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Organism:non-human primate· 2 Research Focus:benchmarking· 1

Frequent Co-Authors

S. N. Tucker· 4 shared N. Peinovich· 3 shared S. N. Tedjakusuma· 3 shared A. C. Moore· 2 shared B. A. Flitter· 2 shared C. A. Lester· 2 shared C. I. Martinez· 2 shared E. D. Neuhaus· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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4 shared papersImmunology

S. N. Tucker

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5 papers

Recent·Most cited

Elimination of human papillomavirus 16-induced tumors by a mucosal rAd5 therapeutic vaccination in a pre-clinical study

M. R. Braun, J. D. Lindbloom, A. C. Moore, K. A. Hodgson, E. G. Dora, S. N. Tucker

This study shows that mucosal rAd5 vaccines targeting HPV16 E6 and E7 proteins reduce tumor volume and improve survival in a mouse model of HPV-induced cancer.

bioRxiv · Mar 11, 2024 · PreprintImmunology

Adenoviral-Based Vaccine Elicits Robust Systemic and Mucosal Cross-Reactive Responses in African Green Monkeys and Reduces Shedding after SARS-CoV-2 Challenge

S. N. Tedjakusuma, C. A. Lester, E. D. Neuhaus, E. G. Dora, S. N. Tucker, B. A. Flitter

This study evaluates a mucosal rAd5 vaccine in African green monkeys, showing robust cross-reactive immunity and reduced viral shedding after SARS-CoV-2 challenge.

bioRxiv · Dec 19, 2022 · PreprintImmunology

Mucosal Immunization of Cynomolgus Macaques with Adenoviral Vector Vaccine Elicits Neutralizing Nasal and Serum Antibody to Several SARS-CoV-2 Variants

B. A. Flitter, C. A. Lester, S. N. Tedjakusuma, E. G. Dora, N. Peinovich, M. Cortese, C. I. Martinez, C. B. Jegede, E. D. Neuhaus, S. N. Tucker

This study evaluates mucosal immunization with SARS-CoV-2 adenoviral vaccines in macaques, finding that a Wuhan-specific vaccine induces strong cross-reactive serum and nasal antibody responses against multiple variants.

bioRxiv · Feb 21, 2022 · PreprintImmunology

Oral and intranasal Ad5 SARS-CoV-2 vaccines decrease disease and viral transmission in a golden hamster model

S. N. Langel, S. Johnson, C. I. Martinez, S. N. Tedjakusuma, N. Peinovich, E. G. Dora, P. J. Kuehl, H. Irshad, E. G. Barrett, A. Werts, S. N. Tucker

This study shows oral and intranasal Ad5 SARS-CoV-2 vaccines reduce disease severity and viral transmission in golden hamsters.

bioRxiv · Oct 3, 2021Immunology

Pre-clinical studies of a recombinant adenoviral mucosal vaccine to prevent SARS-CoV-2 infection

A. C. Moore, E. G. Dora, N. Peinovich, K. P. Tucker, K. Lin, M. Cortese, S. Tucker

This study evaluates mucosal adenovirus vaccines against SARS-CoV-2, showing that full-length spike antigen induces stronger neutralizing antibodies and T-cell responses compared to partial antigens in mice.

bioRxiv · Sep 4, 2020 · PreprintImmunology