Author

C. A. Lester

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:drug response / drug discovery· 2 Organism:non-human primate· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B. A. Flitter· 2 shared E. D. Neuhaus· 2 shared E. G. Dora· 2 shared S. N. Tedjakusuma· 2 shared S. N. Tucker· 2 shared A. Hargil· 1 shared A. Malkovskiy· 1 shared A. Ramesh· 1 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersImmunology

B. A. Flitter

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Author profile →

3 papers

Recent·Most cited

Adenoviral-Based Vaccine Elicits Robust Systemic and Mucosal Cross-Reactive Responses in African Green Monkeys and Reduces Shedding after SARS-CoV-2 Challenge

S. N. Tedjakusuma, C. A. Lester, E. D. Neuhaus, E. G. Dora, S. N. Tucker, B. A. Flitter

This study evaluates a mucosal rAd5 vaccine in African green monkeys, showing robust cross-reactive immunity and reduced viral shedding after SARS-CoV-2 challenge.

bioRxiv · Dec 19, 2022 · PreprintImmunology

Mucosal Immunization of Cynomolgus Macaques with Adenoviral Vector Vaccine Elicits Neutralizing Nasal and Serum Antibody to Several SARS-CoV-2 Variants

B. A. Flitter, C. A. Lester, S. N. Tedjakusuma, E. G. Dora, N. Peinovich, M. Cortese, C. I. Martinez, C. B. Jegede, E. D. Neuhaus, S. N. Tucker

This study evaluates mucosal immunization with SARS-CoV-2 adenoviral vaccines in macaques, finding that a Wuhan-specific vaccine induces strong cross-reactive serum and nasal antibody responses against multiple variants.

bioRxiv · Feb 21, 2022 · PreprintImmunology

Hyaluronan Synthesis Inhibition Impairs Antigen Presentation and Delays Transplantation Rejection

P. L. Marshall, N. Nagy, G. Kaber, G. L. Barlow, A. Ramesh, B. J. Xie, M. H. Linde, N. L. Haddock, C. A. Lester, Q.-L. Tran, C. R. de Vries, A. Malkovskiy, I. Gurevich, H. Martinez, H. F. Kuipers, , P. L. Bollyky

This study shows that inhibiting hyaluronan synthesis with 4MU impairs antigen presentation and delays transplant rejection in mice and human T-cell reactions.

bioRxiv · Aug 28, 2020Immunology