Author

S. N. Langel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Immunology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Research Focus:host-pathogen & immune response· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

M. Blasi· 3 shared S. R. Permar· 3 shared A. Werts· 2 shared E. G. Barrett· 2 shared H. Irshad· 2 shared P. J. Kuehl· 2 shared T. Travieso· 2 shared C. Garrido· 1 shared

Activity by Year

2021-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersImmunology

M. Blasi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Design and validation of an exposure system for efficient inter-animal SARS-CoV-2 airborne transmission in Syrian hamsters

P. J. Kuehl, J. Dearing, A. Werts, J. Cox, H. Irshad, E. G. Barrett, S. Tucker, S. N. Langel

This paper designs and validates an exposure system for efficient SARS-CoV-2 airborne transmission in Syrian hamsters, showing similar virological outcomes between 1:1 and 1:4 infected-to-naive ratios.

bioRxiv · Nov 18, 2022Microbiology

Distinct upper airway epithelium interferon-stimulated and profibrotic gene expression between adult and infant rhesus macaques infected with SARS-CoV-2

S. N. Langel, C. Garrido, C. Phan, T. Travieso, T. DeMarco, Z.-M. Ma, J. R. Reader, K. J. Olstad, R. L. Sammak, Y. Shaan Lakshmanappa, J. W. Roh, J. Watanabe, J. Usachenko, R. Immareddy, R. E. Pollard, , M. Blasi

This study compares SARS-CoV-2 infection effects in adult and infant rhesus macaques, finding distinct interferon-stimulated and profibrotic gene expression patterns in upper airway epithelium.

bioRxiv · Feb 12, 2022Immunology

Oral and intranasal Ad5 SARS-CoV-2 vaccines decrease disease and viral transmission in a golden hamster model

S. N. Langel, S. Johnson, C. I. Martinez, S. N. Tedjakusuma, N. Peinovich, E. G. Dora, P. J. Kuehl, H. Irshad, E. G. Barrett, A. Werts, S. N. Tucker

This study shows oral and intranasal Ad5 SARS-CoV-2 vaccines reduce disease severity and viral transmission in golden hamsters.

bioRxiv · Oct 3, 2021Immunology

Protective transfer: Maternal passive immunization with a rotavirus-neutralizing dimeric IgA protects against rotavirus disease in suckling neonates

S. N. Langel, J. T. Steppe, J. Chang, T. Travieso, H. Webster, C. Otero, L. Williamson, J. E. Crowe, H. Greenberg, H. Wu, C. Hornik, K. Mansouri, R. Edward, V. Stalls, P. Acharya, , S. R. Permar

bioRxiv · Sep 21, 2021Immunology

Oral Hsp90 inhibitor, SNX-5422, attenuates SARS-CoV-2 replication and dampens inflammation in airway cells.

R. Goswami, V. S. Russell, J. J. Tu, P. Hughes, F. Kelly, S. N. Langel, J. Steppe, S. M. Palmer, T. Haystead, M. Blasi, S. R. Permar

This study shows that the Hsp90 inhibitor SNX-5422 reduces SARS-CoV-2 replication and inflammation in airway cells, suggesting its potential as an early therapeutic.

bioRxiv · Feb 23, 2021Microbiology