Author

H. Irshad

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Microbiology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:drug response / drug discovery· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

P. J. Kuehl· 3 shared A. Werts· 2 shared E. G. Barrett· 2 shared S. N. Langel· 2 shared A. Nayak· 1 shared A. Tomkinson· 1 shared A. Vijjapurapu· 1 shared B. Goyal· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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3 shared papersBiochemistry

P. J. Kuehl

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Discovery and Synthesis of GS-7682, a Novel Prodrug of a 4'-CN-4-Aza-7,9-Dideazaadenosine C-Nucleoside with Broad-Spectrum Potency Against Pneumo- and Picornaviruses and Efficacy in RSV-Infected African Green Monkeys.

D. S. Siegel, H. C. Hui, J. Pitts, M. S. Vermillion, K. Ishida, D. Rautiola, M. Keeney, H. Irshad, L. Zhang, K. Chun, G. Chin, B. Goyal, E. Doerffler, H. Yang, M. O. Clarke, , R. L. Mackman

This paper describes the discovery and synthesis of GS-7682, a prodrug with broad antiviral activity against RSV and other viruses, showing efficacy in RSV-infected monkeys.

bioRxiv · Apr 17, 2024 · PreprintBiochemistry

Design and validation of an exposure system for efficient inter-animal SARS-CoV-2 airborne transmission in Syrian hamsters

P. J. Kuehl, J. Dearing, A. Werts, J. Cox, H. Irshad, E. G. Barrett, S. Tucker, S. N. Langel

This paper designs and validates an exposure system for efficient SARS-CoV-2 airborne transmission in Syrian hamsters, showing similar virological outcomes between 1:1 and 1:4 infected-to-naive ratios.

bioRxiv · Nov 18, 2022Microbiology

Oral and intranasal Ad5 SARS-CoV-2 vaccines decrease disease and viral transmission in a golden hamster model

S. N. Langel, S. Johnson, C. I. Martinez, S. N. Tedjakusuma, N. Peinovich, E. G. Dora, P. J. Kuehl, H. Irshad, E. G. Barrett, A. Werts, S. N. Tucker

This study shows oral and intranasal Ad5 SARS-CoV-2 vaccines reduce disease severity and viral transmission in golden hamsters.

bioRxiv · Oct 3, 2021Immunology

Automated Clear Cell Renal Carcinoma Grade Classification with Prognostic Significance

K. Tian, C. A. Rubadue, D. I. Lin, M. Veta, M. E. Pyle, H. Irshad, Y. J. Heng

The paper develops an automated 2-tiered Fuhrman grading system for ccRCC using WSI and clinical data, showing prognostic significance in an extended test set.

bioRxiv · Jun 6, 2019Pathology