Illuminating the Dark Cancer Phosphoproteome Through a Machine-Learned Co-Regulation Map of 26,280 Phosphosites
W. Jiang, E. J. Jaehnig, Y. Liao, T. M. Yaron-Barir, J. L. Johnson, L. C. Cantley, B. Zhang
The paper constructs a co-regulation map of phosphosites using machine learning and phosphoproteomic data, revealing kinase-substrate associations and identifying potential therapeutic targets in cancer.
bioRxiv · Mar 19, 2024 · PreprintCancer Biology