E. J. Verbeke

Self Fourier shell correlation: properties and application to cryo-ET

The paper extends the Fourier shell correlation (FSC) to estimate resolution and denoise data from a single measurement in cryo-ET.

Cross-seeding Controls Aβ Fibril Populations and Resulting Function

This study investigates how cross-seeding of amyloid-beta peptides affects fibril structure and toxicity, showing that mutant seeds influence both structure and cytotoxicity in WT peptides.

Functionalized Mesoporous Silicas Direct Structural Polymorphism of Amyloid-β Fibrils

This paper shows that functionalized mesoporous silicas control the structural polymorphism of Aβ1-40 fibrils, with hydrophobic silicas producing fibrils more similar to those in AD patient samples.

Separating distinct structures of multiple macromolecular assemblies from cryo-EM projections

The paper develops a method to separate distinct macromolecular structures from heterogeneous cryo-EM data by using common lines in a graphical framework, enabling ab initio 3D structure reconstruction without stringent purification.

Snapshots of single particles from single cells using electron microscopy

This paper combines microfluidic single cell extraction with single particle electron microscopy to study protein complexes in C. elegans embryos, revealing ribosome structures and developmental dynamics.

Classification of Single Particles from Human Cell Extract Reveals Distinct Structures

The paper uses shotgun EM combined with mass spectrometry to classify single particles from human cell extracts, revealing native proteasome structures and an unknown ~1 MDa complex.