Author

E. L. Flannery

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

S. A. Mikolajczak· 4 shared A.-M. Zeeman· 2 shared C. H. M. Kocken· 2 shared G. Roma· 2 shared J. Sattabongkot· 2 shared S. Schuierer· 2 shared A. A. Ruberto· 1 shared A. Harupa-Chung· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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4 shared papersCell Biology

S. A. Mikolajczak

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A Drug Repurposing Approach Reveals Targetable Epigenetic Pathways in Plasmodium vivax Hypnozoites

S. P. Maher, M. A. Bakowski, A. Vantaux, E. L. Flannery, C. Andolina, M. Gupta, Y. Antonova-Koch, M. Argomaniz, C.-M. Monica, C. Brice, A. T. Chao, A. K. Chatterjee, W. T. Cheng, E. Chuenchob, C. A. Cooper, , McNama

The paper identifies epigenetic inhibitors active against Plasmodium vivax hypnozoites through drug repurposing screens, showing epigenetic pathways are critical for hypnozoite quiescence.

bioRxiv · Jan 31, 2023 · PreprintCell Biology

Global gene expression of human malaria parasite liver stages throughout intrahepatocytic development

G. Zanghi, H. Patel, N. Camargo, J. L. Smith, Y. Bae, E. L. Flannery, V. Chuenchob, M. E. Fishbaugher, S. A. Mikolajczak, W. Roobsoong, J. Sattabongkot, K. Hayes, A. M. Vaughan, S. H. I. Kappe

This study provides the first comprehensive gene expression profile of Plasmodium falciparum liver stages during in vivo development, revealing key metabolic and regulatory processes.

bioRxiv · Jan 5, 2023 · PreprintMicrobiology

Transcriptional profiling of hepatocytes infected with the replicative form of the malaria parasite Plasmodium cynomolgi

G. Mitchell, G. Roma, A. Voorberg-van der Wel, M. Beibel, A.-M. Zeeman, S. Schuierer, L. Torres, E. L. Flannery, C. H. M. Kocken, S. A. Mikolajczak, T. T. Diagana

This study profiles host gene expression in rhesus macaque hepatocytes infected with Plasmodium cynomolgi, identifying modulated host pathways during malaria infection.

bioRxiv · Jul 18, 2022Microbiology

Persistence of Plasmodium cynomolgi hypnozoites in cynomolgus monkey iPS-derived hepatocytes

M. Pellisson, A.-M. Zeeman, T. Doll, L. Kirchhofer-Allan, S. Schuierer, G. Roma, E. L. Flannery, S. A. Mikolajczak, C. H. M. Kocken, P. Maeser, M. Rottmann, M. Mueller

This study develops an in vitro model using cynomolgus monkey iPS-derived hepatocytes to study Plasmodium cynomolgi hypnozoite formation and liver stage dormancy, aiding drug discovery.

bioRxiv · Nov 16, 2021 · PreprintCell Biology