Author

T. T. Diagana

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 3

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:metabolomics· 1

Frequent Co-Authors

M. P. Barrett· 2 shared A. J. M. Wollman· 1 shared A. P. Waters· 1 shared A. Voorberg-van der Wel· 1 shared A. W. Guiguemde· 1 shared A.-M. Zeeman· 1 shared B. Taft· 1 shared C. Bower-Lepts· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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2 shared papersMicrobiology

M. P. Barrett

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3 papers

Recent·Most cited

MicrobiologybioRxivPreprintOct 3, 2022

A conserved metabolic signature associated with response to fast-acting antimalarial agents

N. V. Simwela, A. W. Guiguemde, J. Straimer…·A. P. Waters

This paper identifies a conserved metabolic signature in malaria parasites exposed to fast-acting antimalarial drugs, suggesting a common mechanism of action.

DOI 10.1101/2022.10.03.510714

plant (other)metabolomics

𝕏 PostBluesky

MicrobiologybioRxivJul 18, 2022

Transcriptional profiling of hepatocytes infected with the replicative form of the malaria parasite Plasmodium cynomolgi

G. Mitchell, G. Roma, A. Voorberg-van der Wel…·T. T. Diagana

This study profiles host gene expression in rhesus macaque hepatocytes infected with Plasmodium cynomolgi, identifying modulated host pathways during malaria infection.

DOI 10.1186/s12936-022-04411-3

ratbulk RNA-seq

𝕏 PostBluesky

MicrobiologybioRxivApr 24, 2019

Targeting the trypanosome kinetochore with CLK1 protein kinase inhibitors

M. Saldivia, S. P. S. Rao, E. Fang…·J. C. Mottram

This study identifies CLK1 as a novel drug target in Trypanosoma brucei by showing its essential role in kinetochore function and cell survival through kinase inhibition.

DOI 10.1038/s41564-020-0745-6

humanexperimental assay

𝕏 PostBluesky