Author

E. Leikina

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Organism:Arabidopsis· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

J. M. Whitlock· 2 shared K. Melikov· 2 shared L. Chernomordik· 2 shared B. Podbilewicz· 1 shared C. Valansi· 1 shared D. Moi· 1 shared E. Matveev· 1 shared H. Romero· 1 shared

Activity by Year

2016-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersCell Biology

J. M. Whitlock

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Author profile →

3 papers

Recent·Most cited

Formation of multinucleated osteoclasts depends on an oxidized species of cell surface associated La protein

E. Leikina, J. M. Whitlock, K. Melikov, W. Zhang, M. P. Bachmann, L. Chernomordik

This study identifies an oxidized form of La protein at the osteoclast surface, driven by ROS signaling, which promotes multinucleation and bone resorption.

bioRxiv · May 2, 2024Cell Biology

Cell Surface-Bound La Protein Regulates The Cell Fusion Stage Of Osteoclastogenesis

J. M. Whitlock, E. Leikina, K. Melikov, L. Fernandez De Castro, S. Mattijssen, R. Maraia, M. Collins, L. Chernomordik

The paper identifies La protein as a cell surface regulator of osteoclast fusion, showing its role in bone metabolism and potential as a therapeutic target.

bioRxiv · Mar 8, 2022Cell Biology

Arabidopsis HAP2/GCS1 is a gamete fusion protein homologous to somatic and viral fusogens

C. Valansi, D. Moi, E. Leikina, E. Matveev, M. Grana, L. V. Chernomordik, H. Romero, P. S. Aguilar, B. Podbilewicz

This paper shows that Arabidopsis HAP2/GCS1 promotes cell-cell fusion and virus-cell fusion, sharing a mechanism with somatic fusogens and viruses, and proposes a new superfamily called FUSEXINS.

bioRxiv · Dec 31, 2016Cell Biology