Author

E. M. Harberts

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

D. Grubaugh· 2 shared I. E. Brodsky· 2 shared R. K. Ernst· 2 shared S. Shin· 2 shared A. R. Bass· 1 shared D. C. Akuma· 1 shared J. Alexander-Floyd· 1 shared J. D. Buxbaum· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 25 mutual co-author links

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2 shared papersImmunology

D. Grubaugh

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2 papers

Recent·Most cited

Position-specific secondary acylation determines detection of lipid A by murine TLR4 and caspase-11

E. M. Harberts, D. Grubaugh, D. C. Akuma, S. Shin, R. K. Ernst, I. E. Brodsky

The paper investigates how position-specific secondary acyl chains on lipid A affect TLR4 and Casp11 activation, revealing distinct structural requirements for each receptor.

bioRxiv · Dec 16, 2021Immunology

Human TLR4 and noncanonical inflammasome differ in their ability to respond to distinct lipid A variants

J. Alexander-Floyd, A. R. Bass, E. M. Harberts, D. Grubaugh, J. D. Buxbaum, I. E. Brodsky, R. K. Ernst, S. Shin

The paper compares how human TLR4 and noncanonical inflammasome sensors CASP4/5 respond to different lipid A structures, finding that acylation state differentially affects their activation.

bioRxiv · Dec 16, 2021 · PreprintImmunology