SARS-CoV-2 infection and replication in human fetal and pediatric gastric organoids
G. G. Giobbe, F. Bonfante, E. Zambaiti, O. Gagliano, B. C. Jones, C. Luni, C. Laterza, S. Perin, H. T. Stuart, M. Pagliari, A. Bortolami, E. Mazzetto, A. Manfredi, C. Colantuono, L. Di Filippo, , P. De Coppi
This paper shows that SARS-CoV-2 can infect and replicate in pediatric gastric organoids but not in fetal ones, suggesting differential susceptibility based on developmental stage.
bioRxiv · Jun 24, 2020Cell Biology