Author

G. G. Giobbe

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:organoid / primary culture· 3 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

P. De Coppi· 4 shared N. Elvassore· 3 shared A. F. Pellegata· 2 shared B. C. Jones· 2 shared D. Cacchiarelli· 2 shared F. Michielin· 2 shared S. Eaton· 2 shared A. A. Straatman-Iwanowska· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersCell Biology

P. De Coppi

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Author profile →

4 papers

Recent·Most cited

Single cell-guided prenatal derivation of primary epithelial organoids from the human amniotic and tracheal fluids.

M. F. M. Gerli, G. Cala, M. A. Beesley, B. Sina, L. Tullie, F. Panariello, F. Michielin, K. Y. Sun, J. R. Davidson, F. M. Russo, B. C. Jones, D. Lee, S. Savvidis, T. Xenakis, I. C. Simcock, , P. De Coppi

The paper derives epithelial organoids from human amniotic and tracheal fluids to model congenital malformations and predict disease outcomes.

Nature Medicine · Mar 4, 2024Peer-reviewedCell Biology

Lung viral infection modelling in a bioengineered whole-organ

F. Tommasini, T. Benoist, S. Shibuya, M. N. J. Woodall, E. Naldi, J. C. Orr, G. G. Giobbe, E. F. Maughan, R. E. Hynds, A. Gjinovci, J. C. Hutchinson, O. J. Arthurs, S. M. Janes, N. Elvassore, C. M. Smith, , P. De Coppi

This paper develops a bioreactor-based whole-organ lung model to study viral infections and demonstrates its use for testing antiviral drugs like Remdesivir.

bioRxiv · Feb 1, 2023Bioengineering

Synchronisation of apical constriction and cell cycle progression is a conserved behaviour of pseudostratified neuroepithelia informed by their tissue geometry

I. Ampartzidis, C. Efstathiou, F. Paonessa, E. M. Thompson, T. Wilson, C. McCann, N. Greene, A. Copp, F. J. Livesey, N. Elvassore, G. G. Giobbe, P. De Coppi, E. Maniou, G. L. Galea

This study shows that neuroepithelial cells synchronize apical constriction with cell cycle progression, but the timing of constriction is influenced by tissue geometry in different regions of the neural tube.

bioRxiv · Jun 15, 2022Cell Biology

SARS-CoV-2 infection and replication in human fetal and pediatric gastric organoids

G. G. Giobbe, F. Bonfante, E. Zambaiti, O. Gagliano, B. C. Jones, C. Luni, C. Laterza, S. Perin, H. T. Stuart, M. Pagliari, A. Bortolami, E. Mazzetto, A. Manfredi, C. Colantuono, L. Di Filippo, , P. De Coppi

This paper shows that SARS-CoV-2 can infect and replicate in pediatric gastric organoids but not in fetal ones, suggesting differential susceptibility based on developmental stage.

bioRxiv · Jun 24, 2020Cell Biology