Author

A. F. Pellegata

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:organoid / primary culture· 2 Research Focus:cell-cell communication· 1 Research Focus:drug response / drug discovery· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1

Frequent Co-Authors

P. De Coppi· 3 shared G. G. Giobbe· 2 shared N. Elvassore· 2 shared N. Thapar· 2 shared S. Eaton· 2 shared V. S. W. Li· 2 shared A. Baulies· 1 shared A. Bortolami· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersBioengineering

P. De Coppi

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Author profile →

3 papers

Recent·Most cited

Lung viral infection modelling in a bioengineered whole-organ

F. Tommasini, T. Benoist, S. Shibuya, M. N. J. Woodall, E. Naldi, J. C. Orr, G. G. Giobbe, E. F. Maughan, R. E. Hynds, A. Gjinovci, J. C. Hutchinson, O. J. Arthurs, S. M. Janes, N. Elvassore, C. M. Smith, , P. De Coppi

This paper develops a bioreactor-based whole-organ lung model to study viral infections and demonstrates its use for testing antiviral drugs like Remdesivir.

bioRxiv · Feb 1, 2023Bioengineering

SARS-CoV-2 infection and replication in human fetal and pediatric gastric organoids

G. G. Giobbe, F. Bonfante, E. Zambaiti, O. Gagliano, B. C. Jones, C. Luni, C. Laterza, S. Perin, H. T. Stuart, M. Pagliari, A. Bortolami, E. Mazzetto, A. Manfredi, C. Colantuono, L. Di Filippo, , P. De Coppi

This paper shows that SARS-CoV-2 can infect and replicate in pediatric gastric organoids but not in fetal ones, suggesting differential susceptibility based on developmental stage.

bioRxiv · Jun 24, 2020Cell Biology

Engineering transplantable jejunal mucosal grafts using primary patient-derived organoids from children with intestinal failure

L. Meran, I. Massie, A. Weston, R. Gaifulina, P. Faull, M. Orford, A. Kucharska, A. Baulies, E. Hirst, J. Konig, A. M. Tedeschi, A. F. Pellegata, S. Eli, A. P. Snijders, L. Collinson, , V. S. W. Li

This study develops a method to create transplantable jejunal mucosal grafts using patient-derived organoids and decellularized scaffolds, demonstrating functional grafts in vitro and in vivo.

bioRxiv · Nov 25, 2019Bioengineering