Author

E. Mulkearns-Hubert

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:flow cytometry· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

C. Horbinski· 2 shared D. Bayik· 2 shared J. D. Lathia· 2 shared J. Volovetz· 2 shared A. G. Alvarado· 1 shared A. Lauko· 1 shared A. Steffens· 1 shared B. W. Kristensen· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersCancer Biology

C. Horbinski

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Author profile →

3 papers

Recent·Most cited

SerpinB3 drives cancer stem cell survival in glioblastoma

A. Lauko, J. Volovetz, S. M. Turaga, D. Bayik, D. C. Watson, D. J. Silver, K. Mitchell, E. Mulkearns-Hubert, K. Desai, M. Midha, J. Hao, K. McCortney, A. Steffens, U. Naik, M. S. Ahluwalia, , J. D. Lathia

This study identifies SerpinB3 as a key driver of glioblastoma cancer stem cell survival and shows that targeting it enhances radiation therapy efficacy in pre-clinical models.

bioRxiv · Dec 21, 2021Cancer Biology

Integrin α6β4 is downregulated in mutant IDH1 oligodendrogliomas, promotes glioma growth, and associates with a worse outcome in glioma patients

R. Stewart, M. Chen, E. Mulkearns-Hubert, J. Lathia, K. O'Connor, C. Horbinski

This study shows integrin α6β4 is downregulated in IDH1 mutant oligodendrogliomas, promotes glioma growth, and is linked to worse patient outcomes.

bioRxiv · Aug 15, 2019 · PreprintCancer Biology

Global immune fingerprinting in glioblastoma reveals immune-suppression signatures associated with prognosis

T. J. Alban, A. G. Alvarado, M. D. Sorensen, D. Bayik, J. Volovetz, E. Serbinowski, E. Mulkearns-Hubert, M. Sinyuk, J. S. Hale, G. R. Onzi, M. McGraw, P. Huang, M. M. Grabowski, C. A. Wathen, T. Radivoyevitch, , J. D. Lathia

The paper identifies immune-suppression signatures in glioblastoma (GBM) patients, showing elevated myeloid-derived suppressor cells (MDSCs) linked to poor prognosis and reduced survival.

JCI Insight · Nov 2, 2018Peer-reviewedCancer Biology