E. Normandeau

Telomere-to-telomere genome assembly of the clubroot pathogen Plasmodiophora brassicae

This paper presents the first telomere-to-telomere genome assembly of Plasmodiophora brassicae, a plant pathogen, and provides a high-quality gene annotation.

Pharmacological control of CAR T cells through CRISPR-driven rapamycin resistance

This study develops a CRISPR-based method to create rapamycin-resistant CAR-T cells, enabling pharmacological control of their activity in cancer therapy.

Comparative Restriction Enzyme Analysis of Methylation (CREAM) Reveals Methylome Variability Within a Clonal In Vitro Cannabis Population

The paper introduces CREAM, a method to assess DNA methylation in cannabis clones, finding preserved methylation patterns across subcultures and identifying epigenetic variability in tissue-cultured cannabis.

Epigenetic and genetic differentiation between Coregonus species pairs

The paper examines genetic and epigenetic differentiation between sympatric benthic-limnetic whitefish species pairs, finding evidence that DNA methylation contributes to mutagenesis and genetic divergence during speciation.

Fish-microbe systems in the hostile but highly biodiverse Amazonian blackwaters

The paper investigates fish-microbe interactions in Amazonian blackwaters, finding host-specific responses and the role of endogenous symbionts in fish survival.

Captive rearing effects on the methylome of Atlantic salmon after oceanic migration: sex-specificity and intergenerational stability

This study examines the epigenetic effects of captive rearing on Atlantic salmon, finding sex-specific methylation changes and limited intergenerational inheritance.

Searching for intra-locus sexual conflicts in the three-spined stickleback (Gasterosteus aculeatus) genome

The paper investigates intra-locus sexual conflicts in three-spined sticklebacks using whole genome sequencing and detects four genomic regions associated with balancing selection, suggesting most conflicts are transient but may locally reduce purifying selection.

Genomic and environmental factors shape gill microbiome activity in an Amazonian teleost holobiont

This study examines how genomic and environmental factors influence gill microbiome activity in Amazonian fish, finding that environmental factors have a stronger impact than host genetics.

Thermal regime during parental sexual maturation, but not during offspring rearing, modulates DNA methylation in brook charr (Salvelinus fontinalis)

The study shows that parental thermal exposure during sexual maturation affects offspring DNA methylation, but offspring rearing temperature does not.

Genome assembly, structural variants, and genetic differentiation between Lake Whitefish young species pairs (Coregonus sp.) with long and short reads

The paper assembles genomes and identifies structural variants in two Lake Whitefish species pairs using long and short reads, finding that SVs cover more genome than SNPs and are linked to transposable elements.

Long distance migration is a major factor driving local adaptation at continental scale in Coho Salmon

This study identifies long-distance migration as a key driver of local adaptation in Coho Salmon across North America, revealing genetic associations with migration and altitude.

Genome-wide DNA methylation predicts environmentally-driven life history variation in a marine fish

This study shows that DNA methylation patterns differ between two life history strategies in capelin, suggesting epigenetic changes, not genetic differences, drive these variations.

Locally-adaptive inversions modulate genetic variation at different geographic scales in a seaweed fly

This study examines how chromosomal inversions influence genetic variation across geographic scales in the seaweed fly, finding they differentiate populations more strongly than collinear regions.

Demographic history shaped geographical patterns of deleterious mutation load in a broadly distributed Pacific Salmon

The paper reconstructs the demographic history of Coho salmon to show how past population dynamics shaped regional differences in deleterious mutation load.

The role of recombination on genome-wide patterns of local ancestry exemplified by supplemented Brook Charr populations

The paper examines how recombination affects local ancestry patterns in Brook Charr populations following hybridization, finding that deleterious mutations influence introgression dynamics.

Adaptive and maladaptive genetic diversity in small populations; insights from the Brook Charr (Salvelinus fontinalis) case study

The paper examines genetic diversity in Brook Charr populations, finding increased deleterious mutations in isolated populations and environmental associations with adaptive loci.

Balancing selection via life-history trade-offs maintains an inversion polymorphism in a seaweed fly

The paper shows that a chromosomal inversion in seaweed flies is maintained by life-history trade-offs and antagonistic pleiotropy, revealing balancing selection mechanisms.

Karyotype-environment associations support a role for a chromosomal inversion in local adaptation among North American populations of the seaweed fly Coelopa frigida

The paper investigates a chromosomal inversion in Coelopa frigida, finding it polymorphic in North America and associated with environmental factors and adult size.