Author

E. Pappas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

H. Thomas· 2 shared X. Liu· 2 shared A. Kallies· 1 shared A. Moreno-Asso· 1 shared B. Krishnamurthy· 1 shared C. Selck· 1 shared C. Smith· 1 shared C.-H. Yang· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

H. Thomas

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2 papers

Recent·Most cited

Extra-islet expression of islet antigen boosts T-cell exhaustion to prevent autoimmune diabetes

C. Selck, G. Jhala, D. De George, C.-T. J. Kwong, M. K. Christensen, E. Pappas, X. Liu, T. Ge, P. Trivedi, A. Kallies, H. Thomas, T. W. H. Kay, B. Krishnamurthy

This study shows that extra-islet antigen exposure leads to T-cell exhaustion, which prevents autoimmune diabetes in NOD mice.

bioRxiv · Feb 12, 2023 · PreprintImmunology

Elevated Neuropeptide Y1 Receptor Signaling Contributes to β-cell Dysfunction and Failure in Type 2 Diabetes

C.-H. Yang, D. Ann-Onda, X. Lin, S. Fynch, S. Nadarajah, E. Pappas, X. Liu, J. Scott, J. S. Oakhill, S. Galic, Y. Shi, A. Moreno-Asso, C. Smith, T. Loudovaris, I. Levinger, , K. Loh

This study shows that increased neuropeptide Y1 receptor signaling contributes to β-cell dysfunction in type 2 diabetes and that inhibiting this receptor with BIBO3304 improves β-cell function and glycaemic control.

bioRxiv · May 14, 2021 · PreprintCell Biology