E. R. Gansemer

Interference with the HNF4-dependent gene regulatory network diminishes ER stress in hepatocytes

The paper identifies HNF4-dependent genes suppressed by ER stress in the liver and shows that HNF4 deletion reduces UPR activation and ER stress.

NADPH and glutathione redox link TCA cycle activity to endoplasmic reticulum stress

The paper shows that TCA cycle activity influences ER stress via NADPH and glutathione redox metabolism in mouse hepatocytes.