Author

M. J. Potthoff

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 4 Research Focus:metabolism & bioenergetics· 3 Research Focus:host-pathogen & immune response· 2 Assay:metabolomics· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

A. Marti· 2 shared C. M. Adams· 2 shared E. D. Abel· 2 shared E. T. Weatherford· 2 shared L. M. G. Pena· 2 shared R. O. Pereira· 2 shared S. H. Bjorkman· 2 shared A. B. Watters· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersPhysiology

A. Marti

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

ATF4 Expression in Thermogenic Adipocytes is Required for Cold-Induced Thermogenesis in Mice via FGF21-Independent Mechanisms

S. H. Bjorkman, A. Marti, J. Jena, L. M. G. Pena, E. T. Weatherford, K. Kato, J. Koneru, J. H. Chen, A. Sood, M. J. Potthoff, C. M. Adams, E. D. Abel, R. O. Pereira

This study shows ATF4 is essential for cold-induced thermogenesis in mice through amino acid metabolism, independent of FGF21, while FGF21 is not required for thermoregulation.

bioRxiv · Mar 9, 2023Physiology

Liver Fibroblast Growth Factor 21 (FGF21) is Required for the Full Anorectic Effect of the Glucagon-Like Peptide-1 Receptor Agonist Liraglutide in Male Mice fed High Carbohydrate Diets

T. D. V. Le, P. Fathi, A. B. Watters, B. J. Ellis, N. Bozadjieva-Kramer, M. B. Perez, A. I. Sullivan, J. P. Rose, L. L. Baggio, J. Koehler, J. L. Brown, M. B. Bales, K. G. Nwaba, J. E. Campbell, D. J. Drucker, , J. E. Ayala

This study shows that FGF21 is necessary for liraglutide's full weight loss effect in male mice on high-carbohydrate diets, mediated through neuronal pathways.

bioRxiv · Jan 3, 2023 · PreprintPhysiology

OPA1 Deletion in Brown Adipose Tissue Improves Thermoregulation and Systemic Metabolism via FGF21

R. O. Pereira, A. Marti, A. C. Olvera, S. M. Tadinada, S. H. Bjorkman, E. T. Weatherford, M. Westphal, P. H. Patel, A. K. Kirby, R. Hewezi, W. Bui Tran, L. M. G. Pena, R. A. Souvenir, M. Mital, C. M. Adams, , E. D. Abel

This study shows that deleting OPA1 in brown adipose tissue enhances thermoregulation and metabolism through the ATF4-FGF21 pathway, independent of thermogenesis.

bioRxiv · Jan 4, 2021Physiology

NADPH and glutathione redox link TCA cycle activity to endoplasmic reticulum stress

E. R. Gansemer, K. S. McCommis, M. Martino, A. Q. King-McAlpin, M. J. Potthoff, B. N. Finck, E. B. Taylor, D. T. Rutkowski

The paper shows that TCA cycle activity influences ER stress via NADPH and glutathione redox metabolism in mouse hepatocytes.

bioRxiv · Oct 29, 2019Cell Biology