Author

D. T. Rutkowski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:cell signaling & trafficking· 2 Approach:wet-lab / biochemical assay· 2 Assay:bulk RNA-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

E. R. Gansemer· 2 shared A. Q. King-McAlpin· 1 shared A. Shah· 1 shared B. N. Finck· 1 shared C. Zhao· 1 shared D. DeZwaan-McCabe· 1 shared E. B. Taylor· 1 shared I. Huck· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersCell Biology

E. R. Gansemer

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3 papers

Recent·Most cited

A beneficial adaptive role for CHOP in driving cell fate selection during ER stress

K. Liu, C. Zhao, R. C. Adajar, D. DeZwaan-McCabe, D. T. Rutkowski

This study shows CHOP promotes cell death in some cells and proliferation in others during ER stress, providing a competitive growth advantage through stress-specific adaptation.

bioRxiv · Mar 19, 2023Cell Biology

Interference with the HNF4-dependent gene regulatory network diminishes ER stress in hepatocytes

A. Shah, I. Huck, K. Duncan, E. R. Gansemer, U. Apte, M. A. Stamnes, D. T. Rutkowski

The paper identifies HNF4-dependent genes suppressed by ER stress in the liver and shows that HNF4 deletion reduces UPR activation and ER stress.

bioRxiv · Feb 9, 2023 · PreprintCell Biology

NADPH and glutathione redox link TCA cycle activity to endoplasmic reticulum stress

E. R. Gansemer, K. S. McCommis, M. Martino, A. Q. King-McAlpin, M. J. Potthoff, B. N. Finck, E. B. Taylor, D. T. Rutkowski

The paper shows that TCA cycle activity influences ER stress via NADPH and glutathione redox metabolism in mouse hepatocytes.

bioRxiv · Oct 29, 2019Cell Biology