Author

E. R. Wright

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 6 Microbiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Assay:cryo-EM· 5 Research Focus:host-pathogen & immune response· 4 Organism:bacteria (other)· 3 Research Focus:cell type annotation· 3 Assay:imaging· 3 Approach:microscopy & imaging analysis· 3 Organism:Drosophila· 2

Frequent Co-Authors

J. E. Yang· 7 shared B. S. Sibert· 4 shared J. Y. Kim· 4 shared D. Parrell· 3 shared J. C. Sanchez· 3 shared M. R. Larson· 3 shared Z. Ke· 3 shared B. Sibert· 2 shared

Activity by Year

2017-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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7 shared papersBiophysics

J. E. Yang

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Integrated Fluorescence Microscopy (iFLM) for Cryo-FIB-milling and In-situ Cryo-ET

J. E. Yang, V. Vrbovska, T. Franke, B. Sibert, M. R. Larson, A. Hall, A. Rigort, J. Mitchels, E. R. Wright

The paper develops an integrated fluorescence microscope module for cryo-FIB-SEM to enable efficient 3D correlative workflows for cryo-ET sample preparation.

bioRxiv · Jul 11, 2023 · PreprintBiophysics

Handling difficult cryo-ET samples: A study with primary neurons from Drosophila melanogaster

J. Y. Kim, J. E. Yang, J. W. Mitchell, L. A. English, S. Z. Yang, T. Tenpas, E. W. Dent, J. Wildonger, E. R. Wright

This study addresses challenges in preparing Drosophila melanogaster neurons for cryo-ET by optimizing substrate selection, micropatterning, data collection, and fixation.

bioRxiv · Jul 10, 2023 · PreprintBiophysics

Atomic-level architecture of Caulobacter crescentus flagellar filaments provide evidence for multi-flagellin filament stabilization

J. C. Sanchez, E. J. Montemayor, N. T. Ploscariu, D. Parrell, J. K. Baumgardt, J. E. Yang, B. Sibert, K. Cai, E. R. Wright

The paper presents an atomic-level structure of Caulobacter crescentus flagellar filaments, revealing molecular interactions and glycosylation sites that contribute to multi-flagellin filament stability and motility.

bioRxiv · Jul 10, 2023 · PreprintBiophysics

Correlative cryogenic montage electron tomography for comprehensive in-situ whole-cell structural studies

J. E. Yang, M. R. Larson, B. S. Sibert, J. Y. Kim, D. Parrell, J. C. Sanchez, V. Pappas, A. Kumar, K. Cai, K. J. Thompson, E. R. Wright

This paper introduces tools for montage electron tomography to improve imaging of large fields of view in cryo-electron tomography while maintaining high-resolution structural information.

bioRxiv · Dec 31, 2021Biophysics

Respiratory syncytial virus matrix protein assembles as a lattice with local and extended order that coordinates the position of the fusion glycoprotein

B. S. Sibert, J. Y. Kim, J. E. Yang, Z. Ke, C. C. Stobart, M. M. Moore, E. R. Wright

This study uses cryo-electron tomography to show RSV matrix protein forms a helical lattice that positions the fusion glycoprotein, providing insights into virion organization and potential vaccine targets.

bioRxiv · Oct 13, 2021 · PreprintBiophysics

Whole-cell cryo-electron tomography of cultured and primary eukaryotic cells on micropatterned TEM grids

B. S. Sibert, J. Y. Kim, J. E. Yang, E. R. Wright

This paper demonstrates the use of micropatterning to culture and adhere eukaryotic cells on TEM grids for whole-cell cryo-ET, enhancing studies of cellular structures and host-pathogen interactions.

bioRxiv · Jun 6, 2021 · PreprintCell Biology

CorRelator: An interactive and flexible toolkit for high-precision cryo-correlative light and electron microscopy

J. E. Yang, M. R. Larson, B. S. Sibert, S. Shrum, E. R. Wright

CorRelator is a cross-platform tool for cryo-correlative light and electron microscopy that enables efficient image and position registration across different microscope systems.

bioRxiv · Aug 6, 2020 · PreprintBiophysics

Flagellar structures from the bacterium Caulobacter crescentus and implications for phage {Phi}CbK predation of multi-flagellin bacteria

E. J. Montemayor, N. T. Ploscariu, J. C. Sanchez, D. Parrell, R. S. Dillard, C. W. Shebelut, Z. Ke, R. C. Guerrero-Ferreira, E. R. Wright

This study investigates how phage {phi}CbK recognizes flagellins in Caulobacter crescentus, showing that multiple flagellins contribute to adsorption and identifying structural features that may influence this interaction.

bioRxiv · Jul 27, 2020Microbiology

Obstruction of pilus retraction stimulates bacterial surface sensing

C. K. Ellison, J. Kan, R. S. Dillard, D. T. Kysela, C. M. Hampton, Z. Ke, E. R. Wright, N. Biais, A. B. Dalia, Y. V. Brun

The paper shows that blocking pilus retraction in Caulobacter crescentus stimulates holdfast synthesis without surface contact, indicating pilus retraction is used for surface sensing.

bioRxiv · Jun 30, 2017Microbiology