J. C. Sanchez

PTEN loss in glioma cell lines leads to increased extracellular vesicle biogenesis and PD-L1 cargo in a PI3K-dependent manner

This study shows PTEN loss increases EV biogenesis and PD-L1 cargo in glioma cells via PI3K signaling, enhancing immunosuppression.

Atomic-level architecture of Caulobacter crescentus flagellar filaments provide evidence for multi-flagellin filament stabilization

The paper presents an atomic-level structure of Caulobacter crescentus flagellar filaments, revealing molecular interactions and glycosylation sites that contribute to multi-flagellin filament stability and motility.

Correlative cryogenic montage electron tomography for comprehensive in-situ whole-cell structural studies

This paper introduces tools for montage electron tomography to improve imaging of large fields of view in cryo-electron tomography while maintaining high-resolution structural information.

Flagellar structures from the bacterium Caulobacter crescentus and implications for phage {Phi}CbK predation of multi-flagellin bacteria

This study investigates how phage {phi}CbK recognizes flagellins in Caulobacter crescentus, showing that multiple flagellins contribute to adsorption and identifying structural features that may influence this interaction.

The Molecular Basis of Specific DNA Binding by the BRG1 AT-hook and Bromodomain

This study identifies the DNA specificity and structural basis of BRG1's composite domain using SELEX-seq, NMR, and modeling, showing how cancer mutations alter DNA binding.