Author

E. Romeis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 6

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Research Focus:cell type annotation· 2 Assay:proteomics· 2 Assay:fluorescence / live-cell microscopy· 1 Assay:long-read sequencing· 1 Research Focus:phylogenetics / evolution· 1

Frequent Co-Authors

L. Giacani· 6 shared A. Haynes· 3 shared A. L. Greninger· 3 shared N. A. P. Lieberman· 3 shared B. Chung· 2 shared L. C. Tantalo· 2 shared M. Eguiluz· 2 shared O. Mitja· 2 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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6 shared papersMicrobiology

L. Giacani

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Bright New Resources for Syphilis Research: Genetically Encoded Fluorescent Tags for Treponema pallidum and Sf1Ep Cells

L. Grillova, E. Romeis, N. A. P. Lieberman, L. C. Tantalo, L. Xu, B. Molini, A. Trejos, G. Lacey, D. Goulding, N. Thomson, A. L. Greninger, L. Giacani

The paper introduces genetically encoded fluorescent tags for Treponema pallidum and Sf1Ep cells to enhance visualization and study host-pathogen interactions in syphilis research.

bioRxiv · May 29, 2024 · PreprintMicrobiology

A Novel Pan-Proteome Array for High-Throughput Profiling of the Humoral Response to Treponema pallidum subsp. pallidum: a Pre-Clinical Study

J. J. Campo, E. Romeis, A. Oberai, J. Pablo, C. Hung, A. Teng, A. D. Shandling, A. Phan, A. Haynes, L. Giacani

This study develops a pan-proteome array to profile the humoral response to Treponema pallidum in rabbits, identifying antigens for early diagnosis and vaccine development.

bioRxiv · Apr 20, 2024 · PreprintMicrobiology

Treponema pallidum subsp. pallidum with an Artificially Impaired TprK Antigenic Variation System is Attenuated in the Rabbit Model of Syphilis

E. Romeis, N. A. P. Lieberman, B. J. Molini, L. C. Tantalo, B. Chung, Q. Phung, C. Avendano, A. Vorobieva, A. L. Greninger, L. Giacani

This study creates a T. pallidum strain with impaired TprK antigenic variation and shows it is attenuated in a rabbit syphilis model.

bioRxiv · Jan 18, 2023 · PreprintMicrobiology

High-throughput nanopore sequencing of Treponema pallidum tandem repeat genes arp and tp0470 reveals clade-specific patterns and recapitulates global whole genome phylogeny

N. A. P. Lieberman, T. D. Armstrong, B. Chung, D. Pfalmer, C. M. Hennelly, A. Haynes, E. Romeis, Q.-Q. Wang, R.-L. Zhang, C.-X. Kou, G. Ciccarese, I. Dal Conte, M. Cusini, F. Drago, S.-i. Nakayama, , A. L. Greninger

The paper uses nanopore sequencing to analyze repeat regions in T. pallidum genes, revealing clade-specific patterns that align with whole genome phylogeny.

bioRxiv · Aug 2, 2022Microbiology

Genetic Engineering of Treponema pallidum subsp. pallidum, the Syphilis Spirochete

E. Romeis, L. Tantalo, N. Lieberman, Q. Phung, A. Greninger, L. Giacani

This paper successfully genetically modifies Treponema pallidum by replacing a pseudogene with a kanamycin resistance cassette, enabling functional genetics studies of syphilis.

bioRxiv · May 7, 2021Microbiology

Transcriptional and immunological analysis of the putative outer membrane protein and vaccine candidate TprL of Treponema pallidum

A. Haynes, M. Fernandez, E. Romeis, O. Mitja, K. Konda, S. Vargas, M. Eguiluz, C. Caceres, J. Klausner, L. Giacani

This paper investigates the transcriptional regulation of the TprL gene in Treponema pallidum, showing that phase variation through homopolymeric G sequences affects its expression and immune response.

bioRxiv · Sep 28, 2020Microbiology