N. A. P. Lieberman

This study identifies mutations conferring resistance to 4-fluorouridine in influenza viruses and shows that resistant variants are attenuated in vivo and can be overcome by higher drug doses.

This study shows that prior respiratory virus infections worsen measles severity in ferrets and that antiviral treatment can mitigate immune amnesia and disease outcomes regardless of treatment timing.

This study creates a T. pallidum strain with impaired TprK antigenic variation and shows it is attenuated in a rabbit syphilis model.

This study compares the efficacy of paxlovid and molnupiravir in preventing SARS-CoV-2 transmission in ferrets, finding that molnupiravir reduces transmission while paxlovid does not.

The paper uses nanopore sequencing to analyze repeat regions in T. pallidum genes, revealing clade-specific patterns that align with whole genome phylogeny.

This study shows that T. pallidum generates TprK sequence diversity both under immune pressure and in vitro without immune selection, highlighting the role of gene conversion in antigenic variation.

This study examines how SARS-CoV-2 induces antiviral host responses, showing differences by viral load, age, and sex in gene expression profiles from infected individuals.

This paper shows SARS-CoV-2 ORF6 interacts with Rae1 and Nup98 to disrupt nucleocytoplasmic transport, reducing reporter expression and causing nuclear mRNA accumulation, more strongly than SARS-CoV ORF6.