Author

B. J. Molini

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

L. Giacani· 4 shared A. L. Greninger· 2 shared A. Vorobieva· 2 shared L. C. Tantalo· 2 shared N. A. P. Lieberman· 2 shared Q. Phung· 2 shared A. Addetia· 1 shared A. Haynes· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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4 shared papersMicrobiology

L. Giacani

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Author profile →

4 papers

Recent·Most cited

Treponema pallidum subsp. pallidum with an Artificially Impaired TprK Antigenic Variation System is Attenuated in the Rabbit Model of Syphilis

E. Romeis, N. A. P. Lieberman, B. J. Molini, L. C. Tantalo, B. Chung, Q. Phung, C. Avendano, A. Vorobieva, A. L. Greninger, L. Giacani

This study creates a T. pallidum strain with impaired TprK antigenic variation and shows it is attenuated in a rabbit syphilis model.

bioRxiv · Jan 18, 2023 · PreprintMicrobiology

In vitro Isolation of Treponema pallidum subsp. pallidum from Fresh and Frozen Needle Aspirates of Primary Experimental Syphilis Lesions

L. C. Tantalo, B. J. Molini, M. Bose, J. D. Klausner, L. Giacani

This paper describes an in vitro method to isolate Treponema pallidum subsp. pallidum from clinical samples without using rabbits.

bioRxiv · Sep 13, 2022Microbiology

B-cell epitope mapping of TprC and TprD variants of Treponema pallidum subspecies

B. J. Molini, M. Fernandez, C. Godornes, A. Vorobieva, S. Lukehart, L. Giacani

This study identifies B-cell epitopes in TprC and TprD variants of Treponema pallidum using pepscan mapping and antisera, showing cross-reactivity and surface-exposed loop targeting.

bioRxiv · Jan 26, 2022 · PreprintMicrobiology

Longitudinal accumulation of in vivo and in vitro-grown Treponema pallidum subsp. pallidum TprK variants in the presence and absence of immune pressure

M. J. Lin, A. Haynes, A. Addetia, N. A. P. Lieberman, Q. Phung, H. Xie, T. V. Nguyen, B. J. Molini, S. A. Lukehart, L. Giacani, A. L. Greninger

This study shows that T. pallidum generates TprK sequence diversity both under immune pressure and in vitro without immune selection, highlighting the role of gene conversion in antigenic variation.

bioRxiv · Jun 26, 2021Microbiology