Author

E. S. Niedzialkowska

Every paper listing this name carries an ORCID.

Identified by ORCID

E. S. NiedzialkowskaiD1 paper · University of Virginia

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell-cell communication· 1 Assay:cryo-EM· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Edward H. EgelmaniD· 2 shared Archit GargiD· 1 shared Dmitri S. KudryashoviD· 1 shared Elena KudryashovaiD· 1 shared Jasper MohiD· 1 shared Jeffrey J ZhouiD· 1 shared Jungsan SohniD· 1 shared Lucas A. RunyaniD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 16 mutual co-author links

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2 shared papersBiophysics

Edward H. EgelmanORCID

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2 papers

Recent·Most cited

BiophysicsThe EMBO JournalPeer-reviewedNov 5, 2025

The atypical filament assembly underpins the inflammasome-independent functions of IFI16.

Archit Garg, Ewa Niedzialkowska, Jeffrey J Zhou…·Jungsan Sohn

This study reveals the structural basis for IFI16's inflammasome-independent functions through cryo-EM and computational analysis of its unique filament assembly.

3 citations

cryo-EMexperimental assay

𝕏 PostBluesky

BiochemistryStructurePeer-reviewedMar 21, 2024

Stabilization of F-actin by Salmonella effector SipA resembles the structural effects of inorganic phosphate and phalloidin

E. S. Niedzialkowska, Lucas A. Runyan, Elena Kudryashova…·Dmitri S. Kudryashov

This study shows that Salmonella effector SipA stabilizes F-actin through a unique binding mechanism, similar to inorganic phosphate and phalloidin, enhancing toxin effects while avoiding host detection.

13 citations

structural biologyexperimental assay

𝕏 PostBluesky