Author

E. S. Xu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

D. G. Kirsch· 2 shared A. J. Wisdom· 1 shared A. R. Daniel· 1 shared C. L. Kent· 1 shared C. S. Hong· 1 shared D. J. Carpenter· 1 shared D. Zhang· 1 shared E. S. Muise· 1 shared

Activity by Year

2020-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersCancer Biology

D. G. Kirsch

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2 papers

Recent·Most cited

Disruption of oncogenic targeting by ISWI via phosphorylation of a prion-like domain

M. Chen, J. P. Foster, I. C. Lock, N. H. Leisenring, A. R. Daniel, W. Floyd, E. S. Xu, I. J. Davis, D. G. Kirsch

The paper shows that ionizing radiation disrupts oncogenic interactions between the fusion oncoprotein FUS-CHOP and the chromatin remodeler ISWI via phosphorylation of FUS-CHOP's prion-like domain, explaining radiation sensitivity in myxoid liposarcoma.

bioRxiv · Mar 11, 2020 · PreprintCancer Biology

A single cell atlas reveals distinct immune landscapes in transplant and primary tumors that determine response or resistance to immunotherapy

A. J. Wisdom, Y. M. Mowery, C. S. Hong, X. Qin, D. Zhang, J. E. Himes, L. Chen, H. Fradin, E. S. Muise, E. S. Xu, D. J. Carpenter, C. L. Kent, K. S. Smythe, N. Williams, L. Luo, , D. G. Kirsch

The paper compares immune landscapes in transplant and primary tumors after immunotherapy and radiotherapy, finding that transplant tumors respond better due to CD8+ T cell enrichment.

bioRxiv · Mar 11, 2020Cancer Biology