Author

E. Scifo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 2 Organism:mouse· 2 Approach:benchmark study· 1 Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

D. Bano· 3 shared D. Ehninger· 2 shared L. Wischhof· 2 shared A. Aziz· 1 shared A. C. Edwards· 1 shared A. Marsal-Cots· 1 shared A. Piazzesi· 1 shared A. Sanz-Moreno· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiochemistry

D. Bano

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

TMEM65-dependent Ca2+ extrusion safeguards mitochondrial homeostasis

M. Vetralla, L. Wischhof, V. Cadenelli, E. Scifo, D. Ehninger, R. Rizzuto, D. Bano, D. De Stefani

This study identifies TMEM65 as a key component of the mitochondrial Ca2+ efflux machinery, showing its role in maintaining Ca2+ homeostasis and preventing mitochondrial dysfunction.

bioRxiv · Oct 10, 2023Biochemistry

Deep Phenotyping and Lifetime Trajectories Reveal Limited Effects of Longevity Regulators on the Aging Process in C57BL/6J Mice

K. Xie, H. Fuchs, E. Scifo, D. Liu, A. Aziz, J. A. Aguilar- Pimentel, O. V. Amarie, L. Becker, P. da Silva-Buttkus, J. Calzada-Wack, Y.-L. Cho, Y. Deng, A. C. Edwards, L. Garrett, C. Georgopoulou, , Schmidt-Weber

This study uses large-scale phenotyping in mice to show that longevity regulators affect age-sensitive phenotypes before detectable aging begins, rather than slowing aging rates.

bioRxiv · Mar 25, 2022Physiology

Comparative profiling of N-respirasomes predicts aberrant mitochondrial bioenergetics at single-cell resolution

F. Bertan, L. Wischhof, E. Scifo, M. Guranda, J. Jackson, A. Marsal-Cots, A. Piazzesi, M. Stork, M. Peitz, J. H. M. Prehn, D. Ehninger, P. Nicotera, D. Bano

The paper develops a method to profile N-respirasomes at single-cell resolution and identifies CHCHD3's role in regulating them, revealing mitochondrial bioenergetic abnormalities.

bioRxiv · Dec 7, 2020 · PreprintCell Biology