Author

A. Sanz-Moreno

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2 Physiology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:cancer & tumor microenvironment· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 3 Approach:experimental assay· 3 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

H. Fuchs· 4 shared B. Rathkolb· 3 shared J. Calzada-Wack· 3 shared M. Hrabe de Angelis· 3 shared T. Klein-Rodewald· 3 shared V. Gailus-Durner· 3 shared L. Becker· 2 shared N. Spielmann· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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4 shared papersPhysiology

H. Fuchs

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

TRPS1 maintains luminal progenitors in the mammary gland by repressing SRF/MRTF activity

M. Tollot-Wegner, M. A. Jessen, K. Kim, A. Sanz-Moreno, N. Spielmann, V. Gailus-Durner, H. Fuchs, M. Hrabe de Angelis, B. von Eyss

This study shows TRPS1 maintains luminal progenitors in the mammary gland by repressing SRF/MRTF activity, linking it to mechanotransduction and breast cancer initiation.

bioRxiv · Nov 24, 2023Cell Biology

New C3H KitN824K/WT cancer mouse model develops late-onset malignant mammary tumors with high penetrance

T. Klein-Rodewald, K. Micklich, A. Sanz-Moreno, M. Tost, J. Calzada-Wack, T. Adler, M. Klaften, S. Sabrautzki, B. Aigner, M. Kraiger, V. Gailus-Durner, H. Fuchs, German Mouse Clinic Consortium, A. Gruender, H. Pahl, , B. Rathkolb

This paper describes a new mouse model with a KIT mutation that develops late-onset mammary tumors with high penetrance and lung metastasis.

bioRxiv · Aug 23, 2022Cancer Biology

Deep Phenotyping and Lifetime Trajectories Reveal Limited Effects of Longevity Regulators on the Aging Process in C57BL/6J Mice

K. Xie, H. Fuchs, E. Scifo, D. Liu, A. Aziz, J. A. Aguilar- Pimentel, O. V. Amarie, L. Becker, P. da Silva-Buttkus, J. Calzada-Wack, Y.-L. Cho, Y. Deng, A. C. Edwards, L. Garrett, C. Georgopoulou, , Schmidt-Weber

This study uses large-scale phenotyping in mice to show that longevity regulators affect age-sensitive phenotypes before detectable aging begins, rather than slowing aging rates.

bioRxiv · Mar 25, 2022Physiology

RANK is an independent biomarker of poor prognosis in estrogen receptor-negative breast cancer and a therapeutic target in patient-derived xenografts

M. Ciscar, E. M. Trinidad, H. Perez-Montoyo, M. Alsaleem, M. J. Jimenez-Santos, M. Toss, A. Sanz-Moreno, A. Vethencourt, G. Perez-Chacon, A. Petit, M. T. Soler-Monso, J. Gomez-Miragaya, C. Gomez-Aleza, M. Jimenez, L. E. Dobrolecki, , E. Gonzalez-Suarez

This study shows RANK is a poor prognosis biomarker in ER-negative breast cancer and that targeting RANK improves outcomes in patient-derived xenografts.

bioRxiv · Dec 13, 2021 · PreprintCancer Biology

Dietary intervention improves health metrics and life expectancy of the genetically obese DU6 (Titan) mouse

A. Mueller-Eigner, A. Sanz-Moreno, I. de-Diego, A. Venkateswaran Venkatasubramani, M. Langhammer, R. Gerlini, B. Rathkolb, A. Aguilar-Pimentel, T. Klein-Rodewald, J. Calzada-Wack, L. Becker, S. Palma-Vera, B. Gille, I. Forne, A. Imhof, , S. Peleg

The study characterizes the Titan mouse as a model for metabolically unhealthy obesity and shows that dietary intervention improves its health and extends lifespan.

bioRxiv · May 11, 2020Physiology