A. Aziz

High Throughput Screening with a Primary Human Mucociliary Airway Model Identifies a Small Molecule with Anti-SARS-CoV-2 Activity

This study uses a primary human stem cell-based airway model to screen 2100 compounds and identifies a small molecule effective against SARS-CoV-2 and its Omicron variant.

A conserved lysine/arginine-rich motif in potyviral 6K1 protein is key in engaging autophagy-mediated self-degradation for completing pepper veinal mottle virus infection

This study identifies a conserved lysine/arginine-rich motif in potyviral 6K1 protein that mediates autophagy-mediated self-degradation, essential for viral infection.

Mutating the arginine residue within the FRNK motif of HC-Pro yield highly attenuated strains that confer complete cross protection against telosma mosaic virus (TelMV) in passion fruit (Passiflora edulis)

Deep Phenotyping and Lifetime Trajectories Reveal Limited Effects of Longevity Regulators on the Aging Process in C57BL/6J Mice

This study uses large-scale phenotyping in mice to show that longevity regulators affect age-sensitive phenotypes before detectable aging begins, rather than slowing aging rates.

In vivo imaging of swimming micromotors using hybrid high-frequency ultrasound and photoacoustic imaging

This paper develops a hybrid imaging system combining high-frequency ultrasound and photoacoustic imaging to track magnetically driven micromotors in vivo and ex vivo.

Bacteriophages can be used as infection control agents: A proof-of concept study involving anti-Acinetobacter baumannii phage

This study demonstrates that bacteriophages can effectively reduce XDR Acinetobacter baumannii on solid surfaces, serving as a potential infection control agent.

Comparative genomics confirms a rare melioidosis human-to-human transmission event and reveals incorrect phylogenomic reconstruction due to polyclonality

This paper investigates a rare human-to-human transmission of Burkholderia pseudomallei from mother to child using whole-genome sequencing, revealing polyclonality in the mother and demonstrating how mixture can mislead phylogenomic analysis.

Real-time optoacoustic tracking of single moving micro-objects in deep tissue-mimicking phantoms

This paper demonstrates real-time tracking of moving micro-objects in tissue-mimicking phantoms using multispectral optoacoustic tomography.

Molecular signatures of non-typeable Haemophilus influenzae lung adaptation in paediatric chronic lung disease

This study identifies convergent transcriptional adaptations in non-typeable Haemophilus influenzae strains isolated from paediatric chronic lung disease patients.