Author

E. V. Vinogradova

Sirius University of Science and Technology

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Immunology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:drug response / drug discovery· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Assay:electrophysiology· 1 Organism:virus· 1

Frequent Co-Authors

Anna ShulmaniD· 1 shared B. F. Cravatt· 1 shared B. Melillo· 1 shared B. T. Chait· 1 shared C. D. Warren· 1 shared C. Webster· 1 shared D. J. Huggins· 1 shared Diana E. SabirovaiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperPhysiology

Anna ShulmanORCID

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Author profile →

3 papers

Recent·Most cited

Neurophysiological mechanisms of immersive virtual reality influence segmental motor reflexes

Maxim E. Baltin, Anna Shulman, Margarita Nikulina, E. V. Vinogradova, Dmitry Onishchenko, Diana E. Sabirova, Tatyana Baltina

This study investigates how emotionally charged immersive VR affects spinal reflex excitability in healthy adults, finding differential effects on dominant and non-dominant limbs.

bioRxiv · Nov 26, 2025 · PreprintPhysiology

Covalent Targeting of Splicing in T Cells.

K. A. Scott, H. Kojima, N. Ropek, C. D. Warren, T. L. Zhang, S. J. Hogg, C. Webster, X. Zhang, J. Rahman, B. Melillo, B. F. Cravatt, J. Lyu, O. Abdel-Wahab, E. V. Vinogradova

This study develops chemical probes to target splicing factors in T cells, showing state-dependent loss of ITK via SF3B1 and demonstrating covalent ligandability of splicing regulators.

bioRxiv · Dec 18, 2023Immunology

Using a function-first "scout fragment"-based approach to develop allosteric covalent inhibitors of conformationally dynamic helicase mechanoenzymes

J. R. Ramsey, P. M. M. Shelton, T. K. Heiss, P. D. B. Olinares, L. E. Vostal, H. Soileau, M. Grasso, S. Warrington, S. Adaniya, M. Miller, S. Sun, D. J. Huggins, R. W. Myers, B. T. Chait, E. V. Vinogradova, T. M. Kapoor

The paper develops covalent inhibitors for conformationally dynamic helicases using electrophilic scout fragments and a function-first approach, targeting SARS-CoV-2 nsp13 and human helicases BLM and WRN.

bioRxiv · Sep 25, 2023Biochemistry