Dysregulated heparan sulfate proteoglycan metabolism promotes Ewing sarcoma tumor growth
E. Vasileva, M. Warren, T. J. Triche, J. F. Amatruda
This study develops a zebrafish model of Ewing sarcoma and identifies heparan sulfate proteoglycan metabolism as a driver of tumor growth, showing that targeting this pathway reduces tumorigenicity.
bioRxiv · May 25, 2021Cancer Biology