Cellular mechanisms underlying beneficial versus detrimental effects of bacterial antitumor immunotherapy
J. G. Castillo, S. Fernandez, T. Campbell, D. Gonzalez-Ventura, J. Williams, J. Ybarra, N. F. Hernandez, E. Wells, D. A. Portnoy, M. DuPage
This study investigates how different routes of Listeria monocytogenes administration affect tumor growth in mice, finding that IV followed by IT administration controls tumor growth through anti-Lm CD8 T cells.
bioRxiv · Feb 15, 2024 · PreprintImmunology